Only if your cell, tablet, PC accepts the the single end of that cable and your cell, tablet, PC has the Zello app installed on it and you manage to get it to work correctly without issues...
We have had it hang the radio on line, so you will need a fail safe in the radio like setting the time out timer to one minute of key up time... with no automatic reset for ptt function till you figure out how to keep it from keying the radio.
I've tried it hooked up to a repeater, mobile, base control station and a handheld.... the issue existed with all four.... to the point that I took it down and am now working with my own software very similar to zello format/style....
William R Howell,
GMRS License Call Sign: WQYX489
CEO, USGMRS Repeater & Users Group Association
USGMRS Repeater & Users Group Association (usgmrsgroup.club)
FB Group Page: USGMRS Repeater & Users Group