Thanks for the responses! I found a solution and fix to this issue. First go to this link on scannermaster:
Uniden USB Cable. Halfway down the page is information directed at Windows 8 users, however, the download link for the PL2303_Prolific_DriverInstaller_v1.5.0 is no longer active on Uniden's wiki page. To get the 1.5.0 driver, you will need to go here:
PL2303_Prolific_DriverInstaller_v1.5.0.zip download - 2shared (it's a .zip file). Finally, unzip the package and install your driver. That's the process I followed, and all is working fine.