I agree with all previous posts here, just throwing my 2 pennies in the conversation.
Bose computer speakers here...they can accept audio in through a 1/8" plug and can stay plugged into the desktop, as they mix both sources. Loud, deep and detailed audio.
If using the scanner as a base, there's no reason not to run the audio through decent speakers.
In my experience, ALL digital voice modes sound great on good amplified speakers. Even my XTS3000 on P25 sounds fantastic on the powered speakers. I think a lot of folks get their feet wet with portable radios on digital modes (DMR ham, P25 monitoring, etc) forgetting that the same rules apply as analog.
When I graduated from portables to mobiles in ham DMR, I was blown away by the detail and fidelity that the higher powered audios amps and larger speakers afforded. And it's not a "scanner vs real radio" debate. Even "pro" radios benifit from good amplification and speakers (exept for maybe the APX series, which are capable of jet engine-level dbs LOL) . I almost always run my XTS Moto (local P25 trunk scanning) through either the stereo aux input or the desktop speakers.
All the digital codecs provide for great speech reproduction, they just need the proper speakers/amplification to take advantage of what they provide.
Rich KG5RBG