I’ve used VAC 4.10 which I assume is rather similar. In my experience I didn’t have to change any settings in VAC, or even open the program for that matter. It should create a new sound device in Windows during the install. Right click and the little speaker icon next to the clock and select recording devices. Make sure the Virtual Audio Cable Line 1 device is set as the default. And in SDRSharp you are sending the Audio Output to Line 1 (Virtual Audio Cable). DSD should by default listen to the audio on Line 1 and if your default play back device is your speakers then it should playback on your speakers.