Without getting too deep into the details, Los Angeles County is broken into operating areas.
In simple terms without listing every single city, the areas are as follows:
XLA = Westside cities (Beverly Hills, Culver City, Santa Monica)
XLC = Verdugo cities
XLE = Downey cities
XLF = Long Beach
XLG = South Bay cities
Over time as some of these areas have unified radio communications, the naming nomenclature has been adopted to utilize this naming convention as well. This is seen with Verdugo and Downey using their XLC and XLE assignments for frequency numbering.