Any software that needs to run on the computer would be the issue. Some "Windows tablets" don't run a full version of Windows and can only run specific Windows tablet apps. For example, the early Microsoft Surface tablets could only run Windows tablet apps. But, the Microsoft Surface Pro tablets have a full version of Windows 8, 8.1, or 10 and can run anything that a Windows laptop or desktop can run.
Also, the USB port might be an issue. Some Windows tablets only use the USB port for battery charging and maybe file transfer to another computer. Other Windows tablets have full-service USB ports that can interface with other devices provided the proper device driver is loaded. I can use a Microsoft Surface Pro 3 tablet to connect to my Kenwood TH-D72 handheld radio and run APRS or packet programs that access the radio's internal TNC through the USB port.