With the RadioShack/GRE/Whistler models, you should select a P25 AUTO system type for Palmetto 800 TSYS object and leave the trunking tables set to Default. The bandplan tables are transmitted by the system over the control channel and your radio will automatically set the tables according to that broadcast data. That's the "AUTO" part of the system type. There is no need to worry about rebanding or any trunking table settings like there was with the old MOT 800/900 system type.
Palmetto 800 does use rebanded frequencies, but for scanners monitoring P25 systems that broadcast the table information, it's not necessary for us to worry about those settings anymore.
The site you select to monitor is really dictated by which talkgroups you want to listen to. In general, Richland County & Columbia talkgroups are carried on the Richland County site, while Lexington County talkgroups are carried on the Lexington site. Some county talkgroups are carried on both sites at times, but you'd have to monitor for a bit to verify which fall into that category, and those talkgroups may not be carried on the "other site" consistently. State talkgroups, like SCHP and medical helicopters, will generally be heard on both.
Harbison, which is not a simulcast site, carries a mix of each counties' talkgroups. But again, you'd have to monitor it for a while to determine which talkgroups are carried on it, and how consistently they are carried. If you choose the "wrong" site, you may miss traffic during times that no subscribers tuned to that talkgroup are affiliated to that site. The same is true for the Sandy Run site.
You have no control over which site carries which talkgroups.
This is where a decoding application such as Pro96Com comes in handy. You can feed data to it for a few hours or a few days and see which talkgroups are active on a site.
I hope that helps answer your questions.