It's an individual preference thing.
Often what I've seen is a new ham picks a radio at the recommendation of someone else. If they like it, they learn that radio and get comfortable with it. Since the manufacturers use similar interfaces on different radios, a user tends to be most comfortable with that specific interface style.
Short answer, pick one, learn to use it.
After decades of doing this stuff, both as a hobby and a professional, I've ditched all my amateur gear and switched to commercial gear. Some of my favorite radios are the commercial ones that can be programmed to do exactly what I want, nothing more, nothing less. Removing all the whiz and/or bang options and just setting up the radio simply tends to be much more favorable to me. On/Off/Volume, channel change. Lock everything else down.
After playing with amateur gear for a long time, I personally, and my very own opinion (no one else's and before anyone jumps on me, I'm just speaking for myself, so relax…)
I found the Yaesu easy to use. First couple of radios were Yaesu. But I found their microphones to be cheap and would fail after a few years.
I found the Icom's harder to use and especially annoying/over complicated microphones. Way too easy to hit the wrong button and change a function that would be difficult to undo while driving.
Kenwood, As complicated as the others. Annoying remote head, but mic was still on the RF deck stupidity. At least the mics were built off their commercial models and didn't fall apart. Less buttons on the mics to screw up, too.
If I was going to buy another ham only radio, It would probably be a simple single band Kenwood. But I'm not in the market.