I have multiple radios on in separate rooms (opposite ends of the house) 24/7/365. While working at home I often have to turn down a couple to take meetings. When mobile locally, I'll run one unit. When mobile out of town, I'll run 2 units. It gets wild when there's an incident because I can quickly tie up several radios with each locked on separate channels so I can hear it all.
I have my KNG2 P800 and my EFJohnson 5300 for montgomery county on from 4am till around 3pm 5 days a week and mabe 2 to 4 hrs sat and sunday as well. If i have to go anywhere I have an APX7500 and Uniden BCD996p2 on in my van plus i have my KNG2 radio with me as well. Also have the radios programmed to pick up Sussex County in DE when we take a trip to the beach as well.