I have this same radio and had the same problem as did many others. Look it up on youtube as well and you'll get an answer. The internals are not aligned correctly with the case and once programmed for the first time disables all audio (tones, music, any possible sound). Send your radio back to powerwerx for warranty repair. Had I known about this earlier I would have never bothered with them and would have went to wouxun.us
I fixed mine the day I was going to send it back by plugging in a headphone jack and moving around the plug until it looked straight, then it miraciously fixed itself
This is not the first or last time this has happened to someone as you will find out, this is only a uv3d related problem as well