Forgot to mention it before, but thanks for letting us know that the lock-up issue wasn't P25RX firmware related!
My testing of the various versions you put out was why I never got back to you about this! All the testing took quite a while.
I let everything run under all the test versions including this mornings version for extended periods of time and it never froze up at all. I used the computer with btconfig running in the background for all tests as well.
If I moved the P25RX to one of the ASMedia 3.1 ports, it would freeze sometimes very quick after I started using the machine and sometimes not for an hour. That was frustrating trying to narrow it down!
One thing I did not do and may still try was seeing if the physical STMicro serial port also disconnects and disappears from the USB device list when things freeze. I don't know how I forgot that simple thing to watch for. At this point, I only know something interrupts communications between the P25RX and BTCONFIG when it's plugged into either ASMedia 3.1 USB port.
I don't have another machine here with ASMedia 3.1 ports to test so hopefully it's just something odd with my motherboard so others don't have the problem.
My motherboard is a very new Intel based ASUS board (I forget the model). It has several Intel based USB 2.0 and 3.0 ports built on the board and then two ASMedia 3.1 ports also built on the board. One ASMedia port is a USB C port which can be configured in the bios as a standard port or setup for high current charging if the plugged device requests it. I've had that port set to be a normal 3.1 port. I should play with the bios settings for that port and see if I can get things working with the P25RX.
All the Intel ports I tested worked flawlessly with BTConfig and the P25RX so that's where it will sit unless I test more.
I also tested external powered and non-powered USB 2.0 hubs plugged into the motherboards ASMedia and Intel ports.
As before, BTConfig froze when a hub was connected to an ASMedia port but all worked well when the hubs were plugged into any of the Intel ports.