Do you have any recommendations?
I would first try a couple different computers that have RS232. Failing that, a USB-RS232 interface and a couple computers. If you have an RS232 tester with lights, you can see if the RX and TX data lights are flashing.
If the radio is not replying with TX data, then i would suspect the capacitors used for the DC-DC converter(s, +/- 25 V). Change those caps.
Also look to see if the TTL data on the radio side of the RS232 chip is toggling (use a scope). Maybe the problem is the uProcessor???
Failing that:
Do an exhaustive search for the OEM part. A PCR-100 was pretty cheap a few years ago. If it were my PCR-1000, I would try to find an OEM chip, or a substitute chip same pin out, failing that find a chip tah is close and graft it in.