I have been monitoring this frequency, 460.250, from my location in Spartanburg with Win500 for most of the week. I'm getting analog transmissions on CTCSS 127.3, which is Greenville County Sheriff. I'm also getting DMR, CC1 TG 1000, mostly TS1, some TS2. I assume this is Oconee County Sheriff, but it's a remarkably strong signal in Spartanburg, so I imagine the Greenville analog repeater gets some pretty serious interference when both repeaters transmit at the same time.
Unless Cherokee County is also using CTCSS 127.3 along with Greenville (which is very unlikely), it's safe to say that Cherokee County's use of the frequency is by no means a regular occurence.