I had the same problem with my PRO2006, I it was the on/off switch and squelch switch they need to be cleaned. I couldn't figure out what was wrong with my radio, I had checked everything and found nothing wrong then when I played with the squelch everything came back on so I check it some more and determined it was in fact the squelch. I got a syringe from the drugstore filled it with 99% isopropyl alcohol and shot some into the on/off switch and the volume control and the squelch control, problem solved.
Also if you have any problems with the keypad not responding soak a cloth with same solution and wipe off the keypad and it will solve that problem also.
MB