First of all, Q branch shouldn't be selected if it's a V4. Keep it in Quad sampling. Q branch is for older SDRs like the V3. The V4 has a built in upconverter. Ideally, you want your gain to be no higher than 28-36. Especially when it comes to HF, because with HF you aren't trying to pick up longer signals as much as trying to reduce your noise levels. More gain = more noise.
As for harmonics, they're inevitable. You can usually filter the one in the middle out by enabling "Correct IQ" but other than that, they're just there. Even scanners have these so-called birdies due to the internal osculators and other components.
If your antenna works fine on the weather channels, FM, airband, etc. You can rule out the antenna being defective.
The facts are that the included dipole isn't really made for hf. There's many tricks to try and get it working but even that depends on your environment, how close you are to other communications, etc. Your best bet if you don't want to spend a fortune is a long wire. Attach an SMA connector and, even just running one all around your room should do wonders. Attaching a wire to the dipole can be fiddly, not offer a great connection, etc.
Regardless, always make sure your antenna isn't near any metal, power lines, or other major interference. A lot of modern windows these days have this weird coating that makes it hard for any signal penetration. You have a metal roof? That could also mess with it. Move it around your room and find the best place for it. I have my dipole in my closet for the best reception for P25.
If you're trying to get something on that dipole, your best bet would be 80m down in the 3.5mhz range. Honestly, you should be picking up something if you have a decent wire attached to the top radial, even if you can't really hear it. Do NOT put a wire on both radials.
And most importantly of all, since you're using a V4, you DO need to install the drivers into SDR#. I'm not talking about zadig, I'm assuming you've already done that. You need to go here
Releases · rtlsdrblog/rtl-sdr-blog and download the latest release and drop the rtlsdr.dll file into your SDR# directory.