Hi!
I had some time tonight to take your MC4 file and load it into my D72. I did see a typo for the uplink frequency you had as channel 6. I changed it to 145.990 MHz.
Notice the DUP on the display. This is needed for cross-band full-duplex operation, when you are transmitting from the lower VFO (B) and receiving with the upper VFO (A). DUP is activated by pressing the F key, followed by the 0/DUAL key, and only appears when the active VFO is VFO B, and the frequencies in the two VFOs are not in the same band. Make sure to use an earphone, earbuds, headset, etc. in the 2.5mm speaker jack, to avoid the feedback squeal when transmitting with DUP on the screen. You can turn that off, but then you won't be able to operate full-duplex (but can transmit or receive from either VFO).
I made a couple of other tweaks to your MC4 file, besides activating the DUP function. I set the audio balance all the way to VFO A, since for the ISS repeater and other FM satellites you will be hearing downlinks only in VFO A.
The Audio Balance setting is in menu 120, or from the keyboard MENU > RADIO > Audio > Balance.
Then I set the squelch so that it is wide open in VFO A, and fully closed in VFO B. The Audio Balance setting will already keep you from hearing anything from VFO B, but this is added insurance. VFO A:
VFO B:
The last portion of the bar for squelch in VFO B was blinking, and my picture didn't capture when the last couple of bars appeared on screen.
I also attached a ZIP file with just the updated MC4 file in it, which has the updated uplink frequency and the other tweaks for audio balance and squelch in each VFO. Before you load this in your D72, make sure to back up whatever settings you have in your radio. I did that with mine when I tested your file - backed up the current configuration, loaded yours to test, then restored my settings when I was done.
Please let me know how this works for you.
Good luck, and 73!