The cables are based on an old prolific brand chip, and some versions of windows now object to it! For a while, Windows spotted it and actually uninstalled the driver 'to protect you', then they seemed to not check and the latest update now gives you the warning message. If you google prolific usb cable driver - you'll find the old drivers and if you try installing these, it might just get you around the warning. My office computer though, just re-installs the windows one which is newer, and doesn't work.
For what it is worth, I really hate chirp for programming these radios - the manufacturers one has always worked better for me.