Yeah, I agree, sounds like an RF issue. If you are using a handheld into a repeater, there can be a lot of issues with low signal strength.
The "25KHz wideband channels spacing" that you are referring to on the HT-1250 has to do with the RF deviation, or how much space your transmitted signal uses. 25KHz / 5KHz deviation is pretty much the defacto standard for FM amateur radio in VHF, UHF analog.
Setting it to 20KHz / 4KHz deviation is going to make your recovered audio worse. Less deviation will sound quieter on the traditionally wide band radios that most amateurs are using.
The 20KHz channel spacing is the space between channel centers. It varies by location. The ARRL repeater guide used to include a map of the USA and showed the common channel spacing used by individual states. Here where I am, 15KHz is more common between channels:
146.415MHz, 146.430MHz, 146.450MHz, etc.