Not a lot, because if you are manually adding new frequencies, setting the modulation is part of the entry process though they will, when first entered, show as 'Auto". So, if you reset a specific frequency range to use FM or NFM, then when entering a string of frequencies, leaving them as 'Auto' would make them conform to whatever setting you are using for that range,
If you are appending a system from the database, your frequencies will already have a modulation set. If you wanted to change those, then you'd need to change that by editing the list.