there can be a big difference in performance depending on several factors, what your home is made of has much to do with it. Any foil backed insulation in attic walls will definately attenuate RF. The presence of electrical (and newer houses), CAT-5 and other wiring or air conditioners can be a source of RFI.
If you can, it's best to mount the antenna outside. Where is up to you. Ideally the tallest peak in the roofline, AWAY from your AC power inlet (for safety and powerline noise). Install a good lignting arrestor inline (Polyphasers are the Cadillac, they cost, but it's what all the pro's use- go to any commercial site or cell site and that's what you'll see), and ground it properly. Invest in good feedline, for VHF/UHF, LMR400 is about the MINIMUM for anything over 50FT.
An old DirecTV "foot" make a great poor man's antenna mount, that and a 5-10 foot mast, is a cheap and easy way to mount an antenna without too much hassle. But I strongly suggest putting it outside if at all possible. Of course it all depends what you want to talk to and hear. Local repeaters within a few miles, inside the attic might be fine. if you want to get DX on simplex, you need to be outside and as high as possible.