Two frequencies, two repeaters. You need a reciever on the new channel (your current one is busy listening to the original channel), and you need a transmitter for the new channel (your old transmitter is busy transmitting on the old channel).
Oh, if you want to junk the entire system, radios, repeater, and all, you could get a new system with multiple 'channels' on one actual rf channel, CDMA/TDMA style, but I don't think you want to do that. <grin>
You can have one repeater linked to multiple transmitters and receivers, yes, but you don't get seperate channels that way. You get everything mashed onto one channel. What do you actually want to do?