I have two "backyard" repeaters - one on 220, one on 440. They can be fun, and exasperating, sometimes both at the same time!
You may check to see if your coordinating body has allocated any "shared non-protected" repeater pairs. I've seen a few places that do. Those repeater pairs are free-to-use for low-level, low-power repeaters without any coordination. Of course, if you are in an area with relatively little repeater activity you can also pick a pair that is otherwise unused and odds are be just fine for quite a while - coordinating the pair when you decide you're interested enough to bother.
If it's something you are interested in and want to tinker with, go for it. Number of users isn't necessarily important - my 220 repeater has a grand total of one user, me. Very few people in this area have 220 to begin with, and the terrain around me makes my range very short. But it serves my purpose, I have a 2M remote base attached and can chat with people on 2M simplex while I'm wandering about the area with a 50mW handheld.
Do consider the cost, though. Especially if you don't have sufficient tower height to separate the receive and transmit antennas. Duplexers can easily be the most expensive part of the system, unless you get lucky and find some used ones for a good deal. I would probably never have bothered with my 220 repeater if I hadn't gotten a very good deal on the duplexer. Gear for that band is particularly hard to find for any kind of reasonable price.