+1 on what many have said above, battery life will be impacted, but is sometimes necessary. I have experienced Lithium-ion batteries and AN/PRC-148 MBITR radios lock up and sometimes destroy the desk charger by being left on and charging (something Thales did not like me making public many years ago), to being just something that drained a batteries life quicker (Motorola HT-1250's and their batteries for example).
Some radio have battery eliminator AC/DC charger/battery adapters for desk and long term monitoring use, such as the Motorola HT-750/1250/MTX8250's.....sometimes it is necessary to monitor and not have to switch batteries all the time, or carry the radio around. It may be cheaper/easier to use a handheld radio instead of a "mobile" base station as well.
My current employer has many sites where portable radios are kept powered on in chargers for "emergency operations" use.....which means they are just "cooking" batteries and get very little actual use. Even with the warning s on this type of use/abuse, they continue to buy more batteries when needed and just roll with that policy.