The answer depends on what you want to listen to, and where you want the scanner to "live" while being used.
Assuming you want to listen to local public safety agencies, Horry County public safety, along with municipalities, us a APCO 25 Phase I digital trunked radio system. Additionally, this system uses simulcast technology, which means it transmits the same information on the same frequency from mulitple tower sites simultaneously. Unfortunately, this type of radio system is difficult for most consumer scanners to reliably receive.
The Uniden SDS100 and SDS200 would be the "best" options at this time. The SDS100 is a handheld model, while the SDS200 is a base/tabletop/mobile model. Functionally, they are essentially the same. If you want the ability to easily and quickly move the scanner from one location to another, select the handheld/battery powered SDS100. If it's mostly going to remain stationary, select the SDS200.
Generally speaking, the Horry County radio system is fairly easy to receive signal-wise throughout the county. But if the scanner is located indoors, there may be signal strength issues. You may require an after--market specialized antenna. You won't know that until you receive the scanner, program it, and test it in its intended use area.
There are other options for simulcast. The Unication series of pagers is one such option. They only come in handheld models but can be used in a semi-permanent charging cradle. The Unications have some limitations in functionality as compared to the SDS line of scanners, but those may not be significant in your use case. There are also several computer software applications that can be used in conjunction with SDR dongles (small radio receiver in a USB form factor). These software/SDR options are a bit more complicated to set up than a traditional scanner, but are also notably less expensive.
Hope this helps. Good luck in your research. If you can provide more details of your intended use, we can provide more specific answers.