Does your Mac have an Intel chip or M1/M2 ("Apple Silicon")? If it has an Intel Chip you can run BootCamp which is a more direct way to run Windows on the hardware. This however means you need to restart to change from Windows to Mac. Apple Silicon does not work with BootCamp so Parallels is the way to go.
Most issues with radio programming on the Mac have to do with the USB cable being assigned to either the Windows installation or the Mac. The first time it is plugged in while Windows is running in Parallels it should ask which OS gets it. If not then go into the Parallels Menu Bar icon and select USB Devices and assign it to Windows. Most of the time if this is done properly it will show up in the Windows Device Manager and self-install the driver. If not then go into Device Manager and install the driver yourself like any other Windows device.
One other thing I have noticed is that using a card reader for the SD Card seems to work better than connecting the radio to the computer, it seems more reliable and a lot faster.
I have used Parallels with all of my recent Mac's, including my M1 MBP's, Mini and iMac as well as a dozen or so prior Intel Mac's. I currently run Windows 11 on both my Mi MBP and Intel MBP with Sentinel and other Windows programs and have had no real issues.