I am running 16 Uniden scanners (8 BCT15, 4 BCT15X and 4 BCD996P2), 4 GRE PSR600's and an R8500 (All in my server rack) off of a single ST-2 in my attic.
I have the antenna feeding a Stridsberg 4-port MCA204 multicoupler. This in turn serves 2 Stridsberg 8-port MCA208's going to to the 16 Uniden scanners. Then there is a MCA804 4-port 7/800 MHz. multicoupler feeding the 4 PSR600's. The remaining port on the MCA204 goes to the R8500.
This seems to be working very well, I have had it this way for a few weeks and have had no issues. I really cannot tell any difference with the antenna directly connected to the scanner or thru the 2 multicouplers.
I also have an additional 8-port MCA208 mounted on the rear of my 4-scanner desk mount serving my SDS200, SDS100, 2 BCD996XT's and a PSR400 on my desk. It goes to another ST-2 in the attic.