If it was me, I'd program "Auto" for modulation as a starting point. The exception would be if I knew from a reputable source on the specific type of modulation used (AM, FM Narrow FM, etc.), then I'd use that. (The RR database may have this in the Mode column).
For Auido Option, I'd use "All". Like the above, if I knew for sure whether it was analog or digital, then I'd use the specific.
Of course there is no harm in experimenting with different settings to see which works or which works best. All it would take is the time and effort to make the changes.