There are posts in the CSX Garrett/Willard Sub Railfans Facebook group about this. It's not box cars. It's containers. Reportedly, it was Q010 which is a container train from Bedford Park IL to Port Newark NJ. Reportedly, 15 cars were involved.
In some of the photos, you can see containers sitting across the tracks, containers with caved-in side walls, containers stacked three high in someone's back yard, and well cars (the cars that the containers sit in) with no axles.
There was mention that traffic may be re-routed over Norfolk Southern, but other comments that the wreck would probably be cleaned up pretty quickly.
CSX radio traffic should be on AAR 008 160.230 (road) and AAR 084 161.370 (dispatcher).