I was just looking at an antenna handbook, and apparently the new ones don't have the section on "repeater antenna systems".Just as an idea, if it's possible to separate the antennas vertically rather than horizontally, it may work out better. If you have access to an ARRL antenna handbook, they have charts that show how the vertical separation works. It would be under the repeater antenna section of the book.
At 450 MHz, the book I have shows 30 feet of horizontal spacing gives about 40 Db isolation, vertically about 7 feet of spacing gives the same isolation...
The book however was addressing repeaters where the transmitter is just a few KHz from the receiver.
Your receiver of the radio not transmitting will end up (during the transmission) not being very useful for recepttion, so just don't plan on doing crossband repeat or high duty cycle things (transmitting almost continuously).
Thanks
Joel