All the dot NET versions are designed to coessist. One version doesn't replace an earlier version. .NET is different then .NET Framework. .NET Framework 4.8 which ProScan targets is still supported and doesn't have an end of life date.I have been using 3.5 for several years. I went on MS's .NET d/l page. I didn't see 4.8 anywhere. Even among the list of the no longer supported versions. The only supported version, now, is 9.0